![]() ![]() ![]() ![]() The three of them had successfully lobbied DuPont Merck to reinstate the Endo name for the new generic division.Īmmon and MacDonald had worked together for years and were close friends. MacDonald, in fact, had gone to work for Endo in 1969 before it was acquired by DuPont, and Ammon joined the company four years later, at a time when the old entrepreneurial spirit of the company was still present. Heading Endo was President Carol Ammon, supported by Louis Vollmer, vice-president of sales and marketing, both of whom, along with college friend Mariann MacDonald, head of DuPont Merck's generic-drug manufacturing, had grown up on Long Island, virtually in the shadow of the old Endo plant. Endo also secured the marketing rights to some of the multisource products produced by DuPont Merck, as well as developing its own generics through a strong research and development effort. In December 1994 Endo began distributing products marketed by West Point Pharma, Merck's generic operation. The first successful product offered by Endo Laboratories LLC in May 1994 was cimetidine, a generic equivalent of SmithKline Beecham's Tagamet, followed a few months later by a generic version of Glucotrol. For a company name executives drew on the old Endo name, which surveys showed that despite a decade-long absence was still remembered positively by 85 percent of pharmacists. In the fall of 1993 Dupont Merck decided to achieve some focus by establishing a subsidiary to serve as its generic division. The resulting company proved to be a cipher to customers, who were unsure what to make of its mix of injectable drugs, off-patent brands, and the other products it distributed for other companies. This collaboration led a year later to the two parties creating an independent joint venture, The DuPont Merck Pharmaceuticals Company, to which DuPont contributed its pharmaceutical holdings. In 1989 DuPont and giant pharmaceutical Merck and Company entered into a research and marketing arrangement. Endo began developing other drugs, although in 1983 DuPont decided to stop using the Endo name for its pharmaceutical division. By the early 1980s Endo was generating about $100 million in annual sales, hardly enough to prompt DuPont, which had more than $22 billion in annual sales at the time, to take much notice. Unfortunately Endo's marketing efforts failed to achieve the kind of growth DuPont was looking for in Symmetrel, due in large measure to the bureaucracy of the parent company. The primary reason DuPont acquired Endo was because of its marketing capabilities. Just three years earlier DuPont had become involved in the pharmaceutical industry after one of its researchers developed an antiviral drug called Symmetrel, effective in treating flus. du Pont de Nemours & Company, better known as DuPont. The family-run business eventually relocated to Long Island, and then in 1969 was acquired by E.I. The heritage of the Endo name dates to 1920 when five brothers of the Ushkow family established Endo Laboratories, a small pharmaceutical company, in Manhattan, New York. The company is 60 percent owned by investment firm Kelso & Company. Endo markets its products to primary care physicians and specialists, as well as to other healthcare professionals and retail pharmacies. On the generic side, Endo markets Morphine Sulfate ER (extended release) tablets to treat moderate to severe pain, and Endocet, a generic equivalent to Percocet. The company also offers branded pharmaceuticals to relieve serious coughing and congestion: Hycodan, Hycomine, and Hycotuss. Endo's branded products include Percocet, using oxycodone and acetaminophen to treat moderate to moderately severe pain Percodan, using oxycodone and aspirin to treat less severe pain the Lidoderm patch, used to relieve pain caused by shingles and Frova, using frovatriptan to treat migraines. Endo develops and sells both branded and generic prescription pharmaceuticals, with its manufacturing contracted out to third parties. is a publicly traded company based in the Philadelphia, Pennsylvania area, dedicated to the niche of pain management. ![]()
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